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Because cysteine is relatively scarce in the standard diet, its availability often acts as the bottleneck for glutathione production

In AD, TNF-, oxidative stress, or microbial cues induce keratinocyte necroptosis, resulting in IL-33 release and ILC2 activation, thereby promoting Th2-skewed inflammation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 218.Copp J.P., Desprez P.Y., Krtolica A., Campisi J