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Blanco-Prieto, Isolation methods of large and small extracellular vesicles derived from cardiovascular progenitors: a comparative study

Molinelli et al

General Guidelines for Female Athletes Dose Range : 1020 micrograms (mcg) per day Frequency : 5 days on, 2 days off (or every other day) Timing : Best: Immediately post-workout with carbs and protein Alternate: First thing in the morning, not fasted Cycle Length : 4 to 6 weeks per cycle Off-Cycle : Equal or greater time off (e.g., 46 weeks) This keeps IGF-1 levels elevated without desensitizing receptors or risking long-term metabolic fatigue

Notably, IGF-1 LR3 enhances muscle sensitivity to insulin, thereby promoting glucose uptake and utilization while simultaneously reducing fat storage

Erastin was reported to cause cancer cells to perish via undetermined mechanisms in 2003 [23]