Since the activity of UGT2B7, an enzyme involved in SNAC clearance, is lower in infants compared to adults, higher SNAC plasma levels may occur in neonates and infants
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Because the testing lab carries no commercial stake in the manufacturing outcome, release decisions track the analytical data rather than supplier-side judgement, with acceptance criteria committed in writing before each synthesis run begins
Unopened vials should be kept at room temperature, as freeze thawing, could result in the stability being damaged or reconstitution failure
Other side effects can occur