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Interaction of S100A7 with c-Jun activation domain-binding protein 1 (Jab1), a multifunctional signaling molecule, increases the activity of nuclear factor-B (NF-B) and phosphor-Akt (87, 88)
GM-CSF activates the Jak/STAT pathway to rescue polymorphonuclear neutrophils from spontaneous apoptosis in young but not elderly individuals
The activation of the Wnt/-catenin signaling pathway has been implicated in several types of tumors and hematologic malignancies (Zhang and Wang, 2020)
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