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Formalin-induced nociceptive behavioral test (formalin test) All experiments were prepared as in the previous formalin model study described by Dubuisson and Dennis [9]

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Due to their specialized structural and functional properties, spermatozoa are particularly prone to oxidative damage, which can impair their morphology, motility, and fertilization ability [4]

43 Integrins are generally accepted to adopt at least three distinct conformations: a low-affinity bent conformation, an extended closed conformation with intermediate affinity, and an extended open conformation characterized by high ligand affinity