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It has been argued that the original FTND used to measure dependence among conventional cigarette smokers has limited adaptability to measure dependence among those who use e-cigarettes

Anti-smoking groups argue that this fear is misguided and that tobacco is uniquely pernicious, but all sides agree that the decision made this week is of major importance

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Furthermore, the initial rate of nicotine rise from some high-dose pouches can be as rapid as that from cigarettes, suggesting a potential for dependence similar to other fast delivery nicotine systems (10, 12, 23)