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Immunity 44 , 951953 (2016)

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In pediatric patients with trimethylaminuria (FMO3 deficiency), the use of metronidazole, amoxicillin, and neomycin can partially inhibit the conversion of choline to TMA, with neomycin being the most effective, followed by amoxicillin, and metronidazole being the weakest effective among them

This regulated necrotic cell death is activated in response to Fas/FasL signaling, CD59 ligation combined with pore formation, mediated by ROS, ceramide, and advanced glycation end products (AGEs) [28]