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First, tobacco naturally contains nicotine, an insecticide, which raises alertness, speeds reaction times, and stimulates the release of neurotransmitters such as dopamine, which are associated with pleasure

And so, by law, when we get one of these applications, we have to consider the products impact on existing users of cigarettes and other tobacco products and on nonusers of the product

"The good news is that cigarette smoking has reached unprecedented lows, which is a tremendous public health win, down to 14 percent from over 40 percent in the mid-1960s," said Brian King, senior author of the report and deputy director for research translation at the CDC's Office on Smoking and Health