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Endocrine Reviews, 21(5), 579-607

Remarkably, normalizing the MHCI-MEF2 signalling pathway in cultured MIA neurons prevents the MIA-induced decrease in synapse density

Therefore, diagnosing DILI usually requires ruling out other causes

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Collectively, these findings underscore a close association between the hypoxic microenvironment and the initiation, progression, and severity of SLE