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Merello M, Bhatia KP, Obeso JA

doi: 10.1371/journal.pbio.3002084 150 CaielliSCardenasJde JesusAABaischJWaltersLBlanckJPet al

This was the first clinical study conducted with the Cyanocobalamin/SNAC co-formulation

published in the Journal of Applied Physiology confirmed that BPC-157 significantly accelerated outgrowth of Achilles tendon explants, markedly increased in vitro tendon fibroblast migration in a dose-dependent manner, and substantially increased fibroblast survival under HO-induced oxidative stress establishing a three-part cellular mechanism (outgrowth, migration, survival) that distinguishes BPC-157s tendon repair profile from direct mitogenic agents

At room temperature, peptides are susceptible to degradation through various pathways, including oxidation, hydrolysis, and microbial contamination