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Oral LT4 is absorbed primarily in the small intestine, particularly in the jejunum and ileum, after dissolution in the stomach

In the body, the hypothalamus and pituitary gland are like the control centers for growth hormone release

This is fundamental science that could one day inform the development of next-generation therapies

Increases in extracellular K + mediated by neuronal activities, along with vasoconstrictors such as endothelin 1 (ET1), PDGFB, and blood-derived insulin-like growth factor 1 (IGF1), trigger Ca 2+ entry into pericytes through VGCCs, causing depolarization and contraction [7, 93]

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