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1 Introduction Melanoma, an aggressive form of skin cancer originating from melanocytes, is often driven by genetic mutations, particularly those induced by environmental factors like ultraviolet (UV) radiation ( Nanomaterials, including nanoparticles (NPs), nanogels, liposomes, and micelles, can be engineered for precise drug delivery ( + T cells and boosting targeted anti-tumor responses ( Nanomaterials offer a transformative approach to melanoma immunotherapy, enabling more precise treatment, modulation of the immune microenvironment, and overcoming the limitations of conventional therapies (2426)

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PROTEIN METABOLISM In thyrotoxicosis, protein formation and breakdown are both accelerated

Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons

This increased risk is due to the higher levels of uric acid in the body