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Larazotide can help manage intestinal permeability, while KPV has anti-inflammatory properties that can reduce gut irritation and promote healing

GLP-1 (Glucagon-Like Peptide-1): GLP-1 plays a key role in appetite regulation by promoting satiety and reducing hunger signals

Curcuma longa L. a perennial herb of the Zingiberaceae family, having anti-inflammatory, antioxidant, antitumor, vasoactive, and analgesic effectsis used clinically to treat microcirculation disorders, primary dysmenorrhea, and osteoarthritis, and as an adjuvant treatment for malignant tumors

The non-hormonal mechanism makes them safe to use alongside hormone therapy if desired

doi: 10.1038/s41598-025-18624-4 63 GanesanMWangWMathewsSMakarovENew-AaronMDagurRSet al