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[,] While maternal deprivation-induced elevations in immobilisation durations were overcome by a 20-day intraperitoneal treatment of NAC (20 mg/kg), chronic mild stress-induced depression-like behaviour could not be overcome

308 More recently, treatment with the non-immunosuppressive CypA inhibitor Alisporivir (Debio-025) improved BBB integrity, and prevented development of neuronal loss and cognitive dysfunction in older APOE4 AD mice