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Chemical & Physical Characteristics Compound Class: Small-molecule NNMT inhibitor (quinolinium derivative) Molecular Formula: CHN Appearance: Off-white to pale yellow powder, encapsulated for oral research administration Solubility: Water-soluble

Both groups of sleep-deprived mice were compared to well-rested mice as a control

An important theoretical concern exists: c-Met is overexpressed in multiple human cancers (gastric, lung, colorectal), and chronic c-Met pathway stimulation could potentially influence cancer riskthough this has not been studied longitudinally even in animals

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10.3390/ijms25115842 247 PistoneS.GoycooleaF