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The tobacco industry alone spends about $6 billion annually on point-of-sale advertising and promotions designed to drive sales, Roberts said

also could demonstrate that markers of endothelial function assessed by quantitative cardiovascular magnetic resonance in the peripheral and central vasculature are sensitive to smoking [47]

J Fam Pract 40 : 385394

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Graphical representations of the relationship between smoking behaviour and nicotine dependence typically include a feedback loop