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This also significantly elevated pro-inflammatory factors IL-6, TNF-, and IL-1 in the cerebrospinal fluid, and upregulated lipoxygenase (LOX), PTGS2, IL-6, and TNF- expression in microglial cells, which further promote inflammatory activation

Activation of the P62-keap1-nrf2 pathway protects against ferroptosis in hepatocellular carcinoma cells

By shortening the inflammatory window, BPC-157 treatment might reduce the stimulus for excessive collagen deposition that characterizes problematic scars

The March 2026 MDPI review specifically noted BPC-157's application in burns, skin injuries and soft tissue damage