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48 In a smaller 48-week trial (n = 71) of semaglutide 2.4 mg once weekly in people with biopsy-confirmed MASH and compensated cirrhosis, there was no significant improvement in fibrosis or resolution of MASH compared with placebo

Butyrate upregulated CPT1A expression and activity [51, 73,74,75], potentially modulating cellular succinylation

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