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(2003) Detrimental effects of N(omega) nitro-L-arginine methyl ester (L-NAME) in experimental Escherichia coli sepsis in the newborn piglet

Without rigorous testing, it's unknown if the compounds could have unintended, harmful effects, says Eileen Kennedy, a chemical biologist at the UNC Eshelman School of Pharmacy who studies peptide therapies

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Protocol adherence (consistent dosing intervals, zero missed doses) predicts tissue regeneration outcomes far more reliably than clock-hour optimization