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Use of SSRIs did not appear to influence circulating concentrations of MPO ( p = 0.522), MMP-9 ( p = 0.645), nor TIMP-2 ( p = 0.337)

However, the increase in neurogenesis tends to be higher for larger infarcts, as induced by temporary occlusion of the middle cerebral artery, compared to small, narrowly circumscribed infarcts, such as those induced by photothrombosis (Niv et al., 2012)

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Another study, on MK-677, published in the Journal of Clinical Endocrinology & Metabolism , showed it boosted growth-hormone levels in real live older folks to the normal range found in young adults