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The disorder is caused by a defective or abnormally altered gene that causes one of the proteins responsible for the initial arrest of bleeding (called von Willebrand factor) to be low or not function properly

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10.1016/j.redox.2019.101290 Redox Biol

The endosome is acidic and the level of acidity continues to increase

mellifera ) and worker bees since pollen is their main protein source, and its digestibility and quality might be important nutritive factors that determine reproductive capability (183)