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Based on the cellular copper status, the expression of some molecules involved in copper homeostasis is regulated

In the on-chip co-culture assay, KISPIDMG-105 spheroids showed a significant reduction in viability upon dosage of 1 M cisplatin in the platform containing the on-chip BBB (viability: 79.83 10.24%), compared to the 0.5 M condition (viability: 94.81 9.33%) (Fig

doi: 10.1021/acsomega.8b01360 77

Endokrynol Pol 67:567571 Seitz R, Tmen D, Kunst C et al (2024) Exploring the thioredoxin system as a therapeutic target in cancer: mechanisms and implications

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