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Both activate AMPK, but through distinct mechanisms: metformin inhibits complex I of the mitochondrial electron transport chain, raising the cellular AMP:ATP ratio and thereby activating AMPK indirectly

It is sold for laboratory research, and each ingredient targets the same broad goal from a different angle: cellular energy, metabolism, and the biology of aging

Stage two is a low concentration of B12 in the cell and metabolic abnormalities

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Future research will focus on three directions: Further exploring effects in humans and conducting clinical trials to verify safety and efficacy in human anti-aging, supporting translational application