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Without adequate B12, homocysteine levels rise, and elevated homocysteine is neurotoxic, potentially causing direct damage to nerve cells and blood vessels that supply nerves

For air travel, the medication and injection supplies should be packed in carry-on luggage to maintain temperature control and prevent loss, with a letter from the healthcare provider documenting medical necessity

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Reusing needles introduces both contamination risk and increased discomfort due to dulled needle tips

[246] On March 29, 2018, Schwarzenegger underwent emergency open-heart surgery for replacement of his replacement pulmonic valve