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To evaluate oxidative stress, we assessed lipid and protein oxidation as indicators of cellular damage

[DOI] [PubMed] [Google Scholar] 18.Sharp KG, Yee KM, Steward O

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targeted therapy in RCC)by clarifying disease-specific regulatory mechanisms: PKD1 mutation-driven mitochondrial defects in ADPKD, DPP9-Nrf2-mediated sorafenib resistance in RCC, and PPARFABP1 axis dysregulation in IgA nephropathy, alongside shared core pathways (e.g., GPX4/SLC7A11 as central checkpoints)