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Preclinical research indicates it remains structurally intact in acidic and enzymatic environments, making it a reliable subject for degradation and interaction studies

We identified 60 and 238 patients with and without GHD, respectively

After adjusting the protein concentration using RIPA buffer, an equal amount of total protein (20 g) was resolved on 5% acrylamide gels (Amresco), and proteins were electrophoretically separated on SDS gels (1015%, Sigma) at a constant voltage of 120 V for 20 min ( n = 6 per group)

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Cell 166 , 935949 (2016)