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A third metric is the distal contractile integral (DCI), which is the product of the amplitude, length, and time of the peristaltic wave and is a measure of peristaltic vigor

Iyer, MD Consultant, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota

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Most clinicians recommend starting the ODT at a moderate dose and titrating based on response rather than attempting a direct dose translation

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