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Xanthine oxidase (XO), which participates in purine metabolism, is another key enzymatic source of ROS, producing both superoxide and HO during the conversion of hypoxanthine to xanthine and xanthine to uric acid 50

Separate KPV is sometimes used for short inflammatory events such as an acne flare or post-procedure irritation, then stopped when the event resolves

For a side-by-side of how this compares to the dual and single agonists, see our breakdown of Retatrutide vs Semaglutide vs Tirzepatide