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In the bicyclol treatment experiments, bicyclol was mingled into the Western diet, equating to an oral intake of 50 mg/kg or 200 mg/kg during the respective treatment periods

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An RCT in 72 patients with NAFLD found that NAC (600 mg twice daily) for 3 months significantly improved liver enzymes (ALT, AST) and markers of oxidative stress compared to control, though it did not significantly improve liver histology on biopsy (Khoshbaten et al., Hepat Mon, 2010) [33]

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