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3 Graves' disease as a mechanistic driver of depression Mounting evidence has indicated that GD promotes the development of depression through a variety of mechanisms, including triggering autoimmune responses, inducing hormonal disorders, and influencing the thyroid-gut-microbiome-brain axis

For example, the upregulation of the Nrf2 pathway by lipoic acid in cultured hepatocytes and in the liver of obese or diabetic rats prevented lipid overload-induced steatosis (35) and cell death (36)

FBS was purchased from PAA Laboratories (Austria)

(2001) Mechanism and significance of increased glutathione level in human hepatocellular carcinoma and liver regeneration, FASEB J

Perforating Corneal Injury in Rat and Pentadecapeptide BPC 157