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doi: 10.1021/bi0520737

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Results Molecular analysis reveals structural stability of GRLX and pKa of individual cysteines Given the previous observations that GLRX can be inactivated via an oxidative mechanism 8,23 , herein we sought to investigate the relative vulnerability of each of the individual cysteines towards GSSG, a model glutathionylating agent, or H 2 O 2 and their contribution to oxidative inactivation

10.1046/j.1365-2133.1998.02273.x Br J Dermatol