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Brain metastasis in patients with primary gastrointestinal malignancy on anti-HER2 therapy

Front Oncol 12:991165 Dixon SJ, Lemberg KM, Lamprecht MR, Skouta R, Zaitsev EM, Gleason CE, Patel DN, Bauer AJ, Cantley AM, Yang WS (2012) Ferroptosis: an iron-dependent form of nonapoptotic cell death

Moreover, cyclooxygenases (COX), phospholipase A2, lipoxygenase and cytochrome p450-catalyzed reactions also contribute to the generation of ROS [[9], [10], [11]]