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The nucleus pulposus changes with loss of pressurization, decreased collagen concentration and loss of distinction from annulus fibrosus

FIGURE 2 Iron accumulation is observed after TBI (Raz et al., 2011

Noteworthy, the activation of BDNF signaling is under the control of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) pathway

Its important for patients to consult with their injector to tailor the number and frequency of treatments to their unique needs

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