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In the study by Leyden et al

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It remains unclear, therefore, whether the discrepancy between the initial positive findings and the subsequent failures of replication reflect the small sample sizes in these studies, limitations inherent in the technique employed (especially the use of the compound measure Glx and the relatively low signal-to-noise ratio achieved at low field strength), or a fundamental difference between pediatric and adult OCD

TCE is characterized as carcinogenic to humans based on convincing evidence of a causal association between TCE exposure in humans and kidney cancer