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The impaired blood flow and reduced oxygen supply in the muscles lead to slower repair and regeneration after workouts

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Furthermore, smoking induces several molecular changes, including epigenetic modifications, such as DNA methylation and histone modifications, which can alter the expression of genes involved in immune responses and mucosal integrity

This represents about 200,000 jobs, most of them in the manufacturing sector (133,000)

Data extraction and quality assessment Outcomes data were extracted independently in a pilot tested worksheet by the two investigators (AS and BP) using guidelines by the Cochrane Collaboration