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The levels of CYP27A1 and CYP27B1 were significantly upregulated along with those of VDR mRNA, but CYP24A1 was downregulated in groups supplemented with GSH or its precursor (Fig

In contrast, its concentrations in urine were significantly reduced after storage at -20C

The company is exploring lotiglipron as an alternative oral GLP-1 candidate

For the most up-to-date recommendations specific to dental care, dentists should refer to the Therapeutic Guidelines: Oral and Dental Version 4 , published in late 2025 [1] [3]

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