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In this system, DATS enabled controlled and sustained H 2 S release, offering antioxidant and anti-inflammatory effects

76 GST prodrugs appear to have a more favorable adverse-event profile, given that they are ingested as an inactive compound and undergo breakdown to release cytotoxic metabolites only in the presence of high concentrations of enzymes that occur in the proximity of tumor cells, thereby reducing collateral damage to healthy cells

doi: 10.1016/j.abb.2011.05.001 26 KlarlB

Journal of Manufacturing Science and Engineering, 142 , Article 031006