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Technical limitations also persist in scalable isolation, purification, and characterization methods

The depletion of CCR3 + cells did not affect percentages of DCs (Supplemental Figure 2A) but reduced basophil percentages by 10- to 20-fold (Figure 2A) and entirely inhibited pS6 upregulation in pDCs and cDCs in whole blood stimulated with 10 g/mL anti-IgE antibodies or PN extract (Figure 2B)