MinuteTM Total Protein Extraction Kit for Tendons Pack Size:50 Preps Defects in NLRP3 are the

Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1)

are critical components of the inflammasome that link danger-signals to caspase-1 activation

Bafilomycin A1 (BafA1) is a specific and reversible inhibitor of vacuolar H+-ATPase (V-ATPase) with IC50 values of 4-400 nmol/mg

4 nM (ανβ5) and 14

PD98059 is a ERK1/2 signaling inhibitor

MinuteTM Total Protein Extraction Kit for Tendons Pack Size:50 Preps Defects in NLRP3 are theA tendon ligament is a fibrous connective tissue that attaches muscles to bone. Histologically tendons consist of dense regular collagen fibers that are very tough and notoriously difficult to homogenize. It is also very difficult to lyse the tendon tissues for total protein extraction. Traditional solution based protein extraction methods, such as RIPA, are inefficient and the protein yield is very low. The profile of extracted protein is also biased