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When administered locally and intraperitoneally there were no remarkable changes in motor functioning observed by the researchers [2]

Systemic wound healing or regenerative protocols may use higher doses under physician supervision

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In separate Phase 2 and Phase 3 trials, retatrutide at 12mg produced greater total body weight reduction than semaglutide at 2.4mg across comparable timeframes, with the difference primarily attributable to retatrutides additional glucagon receptor activation