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Aldridge RE, Chan T, van Dalen CJ, Senthilmohan R, Winn M, et al: Eosinophil peroxidase produces hypobromous acid in the airways of stable asthmatics

Interestingly, the incubation with the antioxidant N-acetylcysteine (NAC) upon treatment with NP4 resulted in reduced levels of apoptosis, suggestive that the cytotoxicity of NP4 is related to intracellular redox homeostasis (Supplementary Fig

Like the other peptides in KLOW, KPV is manufactured via Solid-Phase Peptide Synthesis with synthetic amino acids no animal-derived materials

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We also thank Dasman Diabetes Institute for providing training, supervising the laboratory work, and generating data of the biomarkers of redox status