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Across all six studies, the safety findings were consistent: no serious adverse events, no immunogenic responses, no changes in IGF-1, no glucose or insulin disruption

T h 2, T h 17, T h 22, and T fh cells) remain controversial, there is a propensity of evidence to support a clear proatherogenic role for T h 1 cells and an atheroprotective role for Tregs

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Until it reports and a regulator reviews it, there is no approval and no confirmed long-term safety verdict that is the central evidence gap