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Inclusion criteria: Original research ( in vitro , in vivo , and clinical studies) published in English and high-quality reviews were considered first

doi:10.1146/annurev.physiol.64.081501.131029

As an antioxidant, glutathione helps neutralize free radicals and reactive oxygen species, which can cause cellular damage and contribute to various health issues, including liver disease

Mitochondrial biogenesis is a critical cellular process that facilitates the generation of new mitochondria, which is essential for preserving tissue homeostasis

(3) Researchers have investigated whether NNMT inhibition might represent a novel approach to modulating energy expenditure and metabolic health