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The affected individual progressively loses memory and aspects of cognitive and executive function until death, a process that has been aptly named the long goodbye (Dittbrenner, 1994)

Brown, and R

doi: 10.3389/fendo.2022.847401

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The hormone insulin plays a crucial role in promoting the uptake of glucose in adipose and muscle tissue, as well as in synthesizing glycogen in muscle and secreting triglycerides ( As illustrated in Figure 1, MetS is associated with an elevation in oxidative stress, which is the underlying cause of various complications such as atherosclerosis, hypertension, myocardial infarction, and inflammation