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1 H NMR and 13 C NMR spectra were recorded on a FT-NMR JEOL spectrometer at 500 and 125 MHz, respectively, with TMS as an internal standard ( Figures S2A, B )

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Effects are characterized in animal models: potent antinociception, catalepsy at higher amounts, and dose-dependent respiratory and blood-pressure changes typical of a mu-opioid

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