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While most people can obtain sufficient B12 through their diet, certain groups are at higher risk of deficiency and may benefit from supplementation

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Pathogenesis of Portal Hypertension An increase in the hepatic venous pressure gradient (HVPG) the difference between the wedged hepatic venous pressure and the free hepatic venous pressureof at least 10 mm Hg is required for the development of esophageal varices, and an HVPG of 12 mm Hg or more is required for the rupture of esophageal The authors thank Patrick S