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- Symptoms are more common in men and may include: Dark urine Enlarged spleen Fatigue Pallor Rapid heart rate Shortness of breath Jaundice Diagnosis of G6PD Deficiency Hemolytic Anemia: 1-CBC: Bite cells, blister cells, irregular small cells, Heinz bodies, polychromasia

Weight loss of 3 to 6 pounds during this phase is common

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3 Initially, GSH depletion was considered as a by-product of ROS production during mitochondrial permeability during apoptosis via the intrinsic route