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The molecular mechanism may be achieved by inhibiting the ubiquitination of TNF receptor associated factor 6 (TRAF6), the aggregation of TRAF6-TAK1 complex and the activation of MAPKs/NF-B/c-Fos/nuclear factor of activated T cell cytoplasmic 1 (NFATc1) pathway to prevent the differentiation and function of osteoclasts

doi:10.1016/S0021-9258(18)60338-2

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The MeD represents a balanced and complete dietary model, favoring plant-based foods, such as vegetables, whole grains, and EVOO, without excluding animal products, thus ensuring an adequate intake of vitamins and micro- and macronutrients essential for thyroid function