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Due to the absence of systemic suckercides with residual control in organic systems, producers are encouraged to make as many applications as they are comfortable with

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Results indicated that varenicline worked best for normal nicotine metabolizers, whereas NRT patches were most effective for slow metabolizers

30 Nicotine is metabolized primarily to cotinine, which is further metabolized to trans-3-hydroxycotinine (3HC), catalyzed by the liver cytochrome P450 2A6 enzyme