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To this end, we treated cystine-starved cells with GSHee, (a membrane-permeable analog of GSH) and found that GSHee rescued mTORC1 signaling and ISR (Fig

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The authors also emphasized that vitamin K deficiency is not a primary cause of coagulopathy in cirrhosis [48]

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Owing to the rapid reaction between superoxide anions and NO, these so called kindling radicals would lead to the production of ONOO , followed by eNOS uncoupling and subsequent eNOS-mediated superoxide production (bonfire radical, see Figure 2)